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Consumer Review: I Would Like To Explain The Function Of Creatine.
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| I'm a medical student and former user of androstenedione and I also use creatine. I would like to explain the function of creatine. Creatine is produced naturally in the liver Glycine+Arginine->ornithine and guanidinoacetate which is then methylated by S-adenosylmethionine to form creatine. Creatine travels from the liver to other tissues where it is converted to creatine phosphate. ATP phosphorylates creatine to form creatine phosphate. Muscle and brain contain large amounts of creatine phosphate. It provides a small reservoir of high-energy phosphate which can regenerate ATP from ADP. It plays a particularly important role in muscle during the early stages of exercise. After all the creatine is depleted muscle metabolism depends largely in glycogen. This is the reason loading muscles with creatine makes us feel stronger during the first sets.
Creatine later turns into creatinine and is excreted by the kidneys. The amount is proportional to body mass. So , doctors use creatinine as a measure for body mass and renal function. As far as I know, creatine has no effect on stretch receptors in muscles. Stretch receptors are sensors that produce "pain" when the muscles limit it's reached. Many of these supplements are not regulated and few people know how they work and what the long-term effects are. One recommendation is that before you use any supplement, consult a physician or don't only work on your muscles, work on your brain and hit the books! Sorry for the lecture. I hope this information is of usefulness.
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Response #1
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| Thank you for your lecture. I'm serious! I'm trying to talk my dad out of taking Creatine and this will give credence to my arguments against it. I am arguing against it because I see it as a legal steroid, but I don't think it works. We discussed it in one of my pre-requisite courses for the school of Kineisiology at S.F.U. Everything I heard gives me no desire to take it. Thanks again for your enlightening piece.
Sevran
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Response #2
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Creatine and steroids function in vastly different ways. Each are said to promote muscle growth, and each has its own set of risks. You will find great differences in the effectiveness of creatine vs. most steroids (deca, anadrol, you know, the 'real' ones). However, there may very well be real health risks with creatine use. Your concerns for your father are certainly valid.
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